Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.67 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.67 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.67 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.67 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.67 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.67 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.67 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19688701 | 1.00 | GRIN1 (0.67) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL30308938 | 0.88 | GRIN1 (0.61) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL19400462 | 0.88 | GRIN1 (0.61) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL30308901 | 0.88 | GRIN1 (0.61) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL19400501 | 0.88 | GRIN1 (0.61) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL19688879 | 0.88 | GRIN1 (0.61) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL4407465 | 0.88 | GRIN1 (0.61) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL3993491 | 0.88 | GRIN1 (0.61) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL21451995 | 0.87 | GRIN1 (0.60) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL3997047 | 0.86 | SLC6A4 (0.59) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881394-A | Pharmaceutical composition and oral dosage form of ketamine derivative | 凯瑞康宁生物工程（武汉）有限公司 | 2024-04-12 | — | — | CN | disclosed |