Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29209716 | 0.76 | AURKA (0.35) | GAAKMT2AMAPTCHRM4IGF1R | |
| SCHEMBL30881703 | 0.76 | AURKA (0.35) | GAAKMT2AMAPTCHRM4IGF1R | |
| SCHEMBL5184422 | 0.66 | BRD4 (0.34) | GAAMAPTSMN1; SMN2GFER | |
| SCHEMBL17979156 | 0.65 | PDE10A (0.37) | MAPTCYP3A4ALDH1A1LMNACHRM4 | |
| SCHEMBL38659011 | 0.61 | ADORA2A (0.39) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL8817791 | 0.61 | HRH4 (0.50) | SMN1; SMN2 | |
| SCHEMBL25366793 | 0.61 | — | — | |
| SCHEMBL26534302 | 0.61 | CYP1A2 (0.40) | POLBRAB9AMAPTCYP1A2ALDH1A1 | |
| SCHEMBL31446878 | 0.61 | POLB (0.39) | GAAKMT2APOLBMAPTCYP1A2 | |
| SCHEMBL18069384 | 0.60 | CHRM4 (0.41) | CYP1A2ALDH1A1CHRM4TLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |