Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.77 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.60 |
| ▸ | WHR1 | P49842 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PDE5A | O76074 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393626 | 0.98 | MEN1 (0.79) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL30484133 | 0.98 | MEN1 (0.79) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL22058673 | 0.94 | MEN1 (0.80) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL22483256 | 0.94 | MEN1 (0.80) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL16436798 | 0.94 | MEN1 (0.86) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL23606297 | 0.94 | MEN1 (0.86) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL9920500 | 0.91 | MEN1 (0.70) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL19009609 | 0.90 | MEN1 (0.75) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL12014869 | 0.90 | MEN1 (0.69) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL28925268 | 0.89 | MEN1 (0.68) | MEN1KMT2AATMNUDT1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-117736207-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-115362003-B | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |