Propylene Oxide

Propylene Oxide

SCHEMBL29210786

CC1CO1.CCCCC1CNCCO1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.43
ALDH1A1 P00352 1/20 0.41
SLC6A2 P23975 13/20 0.39
SLC6A4 P31645 11/20 0.39
SLC6A3 Q01959 9/20 0.39
HTR2A P28223 3/20 0.39
ADRB2 P07550 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA1A P35348 1/20 0.39
HTR2B P41595 1/20 0.39
ADRA2C P18825 1/20 0.36
BRD4 O60885 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3984484 0.93 EPHX1 (0.48) EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3
Bromide SCHEMBL27075782 0.91 EPHX1 (0.47) EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3
Ammonia Solution, Strong SCHEMBL28772841 0.91 EPHX1 (0.47) EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL28993858 0.91 EPHX1 (0.47) EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3
Propylene Oxide SCHEMBL29210764 0.89 SLC6A2 (0.41) EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL40488 0.87 EPHX1 (0.57) EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL28100468 0.86 EPHX1 (0.43) EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL8657970 0.86 EPHX1 (0.60) EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL4426423 0.86 EPHX1 (0.60) EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL8661751 0.86 EPHX1 (0.60) EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736354-A High-water-solubility cationic cyclodextrin derivative and preparation method and application thereof 南京盛德创赢生物科技有限公司 2024-03-22 CN claimed
CN-117736354-A High-water-solubility cationic cyclodextrin derivative and preparation method and application thereof 南京盛德创赢生物科技有限公司 2024-03-22 CN disclosed