Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2925378 | 0.98 | PLAU (0.55) | PLAUKDM4ELMNAPOLBCASP6 | |
| SCHEMBL18735853 | 0.82 | PLAU (0.59) | PLAUKDM4ELMNAPOLBCASP6 | |
| SCHEMBL7454652 | 0.81 | KDM4E (0.58) | PLAUKDM4ELMNAPOLBCASP6 | |
| SCHEMBL11593729 | 0.81 | PLAU (0.57) | PLAUKDM4ELMNAPOLBCASP6 | |
| SCHEMBL2412433 | 0.78 | HDAC1 (0.47) | KMT2AHRH3HTR3ABACE1DYRK1A | |
| SCHEMBL23759740 | 0.78 | KDM4E (0.55) | PLAUKDM4ELMNAPOLBCASP6 | |
| SCHEMBL1724199 | 0.77 | CYP1A2 (0.57) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL1599323 | 0.77 | BACE1 (0.53) | KDM4ELMNAHTTMEN1KMT2A | |
| SCHEMBL1420330 | 0.77 | BACE1 (0.53) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5765471 | 0.77 | KDM4E (0.53) | PLAUKDM4ELMNAPOLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285651-B1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | TAKEDA PHARMACEUTICAL (JP) | 2010-09-01 | — | — | EP | disclosed |
| EP-1285651-B1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | TAKEDA PHARMACEUTICAL (JP) | 2010-09-01 | — | — | EP | disclosed |