Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13692441 | 0.84 | HTR2C (0.31) | HTR2CSLC6A4DPP4 | |
| SCHEMBL14270122 | 0.81 | HTR2C (0.45) | HTR2CSLC6A4PPARGKAT2BMCL1 | |
| SCHEMBL14635996 | 0.80 | FFAR4 (0.33) | KAT2BMCL1 | |
| SCHEMBL31217671 | 0.79 | SLC6A4 (0.36) | HTR2CSLC6A4PPARGKAT2BMCL1 | |
| SCHEMBL17146957 | 0.79 | SLC6A4 (0.39) | HTR2CSLC6A4PPARGKAT2BMCL1 | |
| SCHEMBL18668473 | 0.78 | PDE2A (0.42) | SLC6A4KAT2BMCL1 | |
| SCHEMBL29571999 | 0.78 | PDE2A (0.42) | SLC6A4KAT2BMCL1 | |
| SCHEMBL16293889 | 0.78 | IDO1 (0.44) | HTR2CSLC6A4PPARGKAT2BMCL1 | |
| SCHEMBL30197140 | 0.78 | IDO1 (0.44) | HTR2CSLC6A4PPARGKAT2BMCL1 | |
| SCHEMBL27562707 | 0.77 | IDO1 (0.40) | HTR2CSLC6A4PPARGKAT2BMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978513-A | Gefitinib-linked triazole derivative and preparation method and application thereof | 河南师范大学 | 2024-11-19 | — | — | CN | claimed |
| CN-117924251-A | Gefitinib-linked triazole derivative and preparation method and application thereof | 河南师范大学 | 2024-04-26 | — | — | CN | claimed |
| CN-118978513-A | Gefitinib-linked triazole derivative and preparation method and application thereof | 河南师范大学 | 2024-11-19 | — | — | CN | disclosed |
| CN-117924251-A | Gefitinib-linked triazole derivative and preparation method and application thereof | 河南师范大学 | 2024-04-26 | — | — | CN | disclosed |