Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK5 | Q8IW41 | 20/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 19/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 18/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24461494 | 0.90 | MAPKAPK5 (0.58) | MAPKAPK5MAPK14MAPK1MAPKAPK2 | |
| SCHEMBL29216076 | 0.90 | MAPKAPK5 (0.58) | MAPKAPK5MAPK14MAPK1MAPKAPK2 | |
| SCHEMBL25751357 | 0.90 | MAPKAPK5 (0.56) | MAPKAPK5MAPK14MAPK1MAPKAPK2 | |
| SCHEMBL29216058 | 0.89 | MAPKAPK5 (0.50) | MAPKAPK5MAPK14MAPK1MAPKAPK2 | |
| SCHEMBL29215965 | 0.88 | MAPKAPK5 (0.54) | MAPKAPK5MAPK14MAPK1MAPKAPK2 | |
| SCHEMBL29963138 | 0.87 | MAPKAPK5 (0.50) | MAPKAPK5MAPK14MAPK1MAPKAPK2 | |
| SCHEMBL24759493 | 0.87 | MAPKAPK5 (0.50) | MAPKAPK5MAPK14MAPK1MAPKAPK2 | |
| SCHEMBL29216049 | 0.87 | MAPKAPK5 (0.47) | MAPKAPK5MAPK14MAPK1MAPKAPK2 | |
| SCHEMBL25783514 | 0.85 | MAPKAPK5 (0.56) | MAPKAPK5MAPK14MAPK1MAPKAPK2 | |
| SCHEMBL29216061 | 0.84 | MAPKAPK5 (0.50) | MAPKAPK5MAPK14MAPK1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444493-A | Derivative containing double parallel rings, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-07-18 | — | — | CN | disclosed |