Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of 4-Methoxy Ethyl Cinnamate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | CA7 | P43166 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | F3 | P13726 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methoxy Ethyl Cinnamate SCHEMBL434842 | 0.97 | CA12 (0.71) | CA12CA1CA2CA7CA9 | |
| 4-Methoxy Ethyl Cinnamate SCHEMBL1056347 | 0.97 | CA12 (0.71) | CA12CA1CA2CA7CA9 | |
| 4-Methoxy Ethyl Cinnamate SCHEMBL15190 | 0.97 | CA12 (0.71) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6340119 | 0.92 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15248923 | 0.92 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| 4-Methoxy Ethyl Cinnamate SCHEMBL28937392 | 0.92 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13957401 | 0.87 | CA12 (0.86) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5059085 | 0.87 | CA12 (0.86) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10939791 | 0.87 | CA12 (0.86) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1238377 | 0.86 | HDAC8 (0.57) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117860678-B | Pharmaceutical composition for treating alcoholic fatty liver and preparation method thereof | 中国农业大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-117860678-A | Pharmaceutical composition for treating alcoholic fatty liver and preparation method thereof | 中国农业大学 | 2024-04-12 | — | — | CN | disclosed |