Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31385834 | 0.81 | MAPT (0.44) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL8337244 | 0.80 | MAPT (0.51) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL1756221 | 0.79 | CA1 (0.50) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL28655785 | 0.77 | MAPT (0.56) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL677961 | 0.76 | CA1 (0.59) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL1756243 | 0.75 | MAPT (0.50) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL28683369 | 0.75 | MAPT (0.50) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL15382437 | 0.75 | CA1 (0.57) | MAPTCA1CA2TDP1CA12 | |
| Water SCHEMBL28249729 | 0.75 | CA1 (0.66) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL14488020 | 0.74 | MAPT (0.49) | MAPTCA1CA2TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940120-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-04-26 | — | — | CN | disclosed |