Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 1/20 | 0.69 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.69 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.69 |
| ▸ | IL2 | P60568 | 15/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15395777 | 0.86 | STIM1 (0.63) | STIM1ORAI1ORAI2IL2L3MBTL1 | |
| Zegocractin SCHEMBL29391484 | 0.82 | STIM1 (1.00) | STIM1ORAI1ORAI2IL2L3MBTL1 | |
| Zegocractin SCHEMBL29362538 | 0.82 | STIM1 (1.00) | STIM1ORAI1ORAI2IL2L3MBTL1 | |
| Zegocractin SCHEMBL18038390 | 0.82 | STIM1 (1.00) | STIM1ORAI1ORAI2IL2L3MBTL1 | |
| SCHEMBL29216902 | 0.81 | STIM1 (0.60) | STIM1ORAI1ORAI2IL2L3MBTL1 | |
| SCHEMBL8260054 | 0.80 | STIM1 (0.67) | STIM1ORAI1ORAI2IL2L3MBTL1 | |
| SCHEMBL17244766 | 0.80 | STIM1 (0.69) | STIM1ORAI1ORAI2IL2L3MBTL1 | |
| SCHEMBL15395969 | 0.80 | STIM1 (0.58) | STIM1ORAI1ORAI2IL2L3MBTL1 | |
| SCHEMBL5554192 | 0.79 | STIM1 (0.57) | STIM1ORAI1ORAI2IL2L3MBTL1 | |
| SCHEMBL5555312 | 0.79 | STIM1 (0.57) | STIM1ORAI1ORAI2IL2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084860-A | Aromatic amide compound, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-28 | — | — | CN | disclosed |