Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29216979 | 1.00 | HTT (0.32) | HTTNPC1GAASMN1; SMN2POLB | |
| SCHEMBL3452538 | 0.88 | POLB (0.32) | POLB | |
| SCHEMBL3452535 | 0.88 | POLB (0.32) | POLB | |
| SCHEMBL24435336 | 0.83 | PTPN2 (0.30) | — | |
| SCHEMBL8948175 | 0.83 | PTPN2 (0.30) | — | |
| SCHEMBL14862053 | 0.79 | HCAR2 (0.39) | — | |
| SCHEMBL14862055 | 0.79 | HCAR2 (0.39) | — | |
| SCHEMBL2505392 | 0.77 | — | — | |
| SCHEMBL2505390 | 0.77 | — | — | |
| SCHEMBL38049 | 0.77 | HTT (0.43) | HTTNPC1GAASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118056834-A | Fused ring pyridone derivatives, preparation method and application thereof | 合肥医工医药股份有限公司 | 2024-05-21 | — | — | CN | disclosed |