Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876034 | 1.00 | CHRM2 (0.37) | CHRM2CHRM1CHRM3HSD17B10PDE8B | |
| SCHEMBL29217081 | 1.00 | CHRM2 (0.37) | CHRM2CHRM1CHRM3HSD17B10PDE8B | |
| SCHEMBL29217067 | 0.89 | TACR1 (0.34) | CHRM2CHRM1CHRM3HSD17B10DPP4 | |
| SCHEMBL21748842 | 0.86 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HSD17B10PDE8B | |
| SCHEMBL38657326 | 0.86 | NR1H2 (0.42) | CHRM2CHRM1CHRM3HSD17B10NR1H2 | |
| SCHEMBL13845953 | 0.86 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HSD17B10PDE8B | |
| SCHEMBL24024276 | 0.84 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HSD17B10NR1H2 | |
| SCHEMBL23950733 | 0.84 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HSD17B10NR1H2 | |
| SCHEMBL23950880 | 0.83 | ATM (0.39) | CHRM2CHRM1CHRM3HSD17B10PDE8B | |
| SCHEMBL24876783 | 0.81 | MEN1 (0.41) | CHRM2CHRM1CHRM3HSD17B10PDE8B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881680-A | Tricyclic compounds as KRAS inhibitors | 因赛特公司 | 2024-04-12 | — | — | CN | disclosed |