Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.65 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12854830 | 0.98 | MAPT (0.68) | MAPTL3MBTL1TDP1LMNAHDAC1 | |
| SCHEMBL2745649 | 0.93 | TDP1 (0.64) | MAPTL3MBTL1TDP1LMNAHDAC1 | |
| SCHEMBL9161621 | 0.90 | HDAC8 (0.61) | MAPTL3MBTL1TDP1LMNAHDAC1 | |
| SCHEMBL317112 | 0.85 | MAPT (0.57) | MAPTL3MBTL1TDP1LMNAHDAC1 | |
| SCHEMBL8519287 | 0.84 | TDP1 (1.00) | MAPTL3MBTL1TDP1LMNAHDAC1 | |
| SCHEMBL9057671 | 0.84 | TDP1 (1.00) | MAPTL3MBTL1TDP1LMNAHDAC1 | |
| SCHEMBL27516050 | 0.84 | TDP1 (1.00) | MAPTL3MBTL1TDP1LMNAHDAC1 | |
| SCHEMBL28052282 | 0.84 | TDP1 (0.74) | MAPTL3MBTL1TDP1LMNAHDAC1 | |
| SCHEMBL7551879 | 0.84 | TDP1 (0.74) | MAPTL3MBTL1TDP1LMNAHDAC1 | |
| SCHEMBL4453533 | 0.83 | SMN1; SMN2 (0.59) | MAPTL3MBTL1TDP1LMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084726-A | 1-Cyano-2-hydroxy-5-fluoro compound and preparation method thereof | 南京工业大学 | 2024-05-28 | — | — | CN | claimed |
| CN-118084726-A | 1-Cyano-2-hydroxy-5-fluoro compound and preparation method thereof | 南京工业大学 | 2024-05-28 | — | — | CN | disclosed |