Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 19/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.41 |
| ▸ | MTOR | P42345 | 12/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30012475 | 1.00 | ATM (0.46) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL29217574 | 0.89 | ATM (0.44) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL30011901 | 0.89 | ATM (0.44) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL30012580 | 0.86 | ATM (0.62) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL30012525 | 0.85 | ATM (0.48) | ATMPIK3CAMTORATR | |
| SCHEMBL29217588 | 0.74 | ATM (0.48) | ATMPIK3CAMTORPIK3CDATR | |
| SCHEMBL30012314 | 0.74 | ATM (0.48) | ATMPIK3CAMTORPIK3CDATR | |
| SCHEMBL30011979 | 0.72 | ATM (0.63) | ATMPIK3CAMTORATR | |
| SCHEMBL30011699 | 0.71 | ATM (0.54) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL30012478 | 0.71 | ATM (0.55) | ATMPIK3CAMTORPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026097-B | Substituted pyrazoloquinazolinone compounds and uses thereof | 上海瑛派药业有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-114026097-A | Substituted pyrazoloquinazolinone compounds and uses thereof | 上海瑛派药业有限公司 | 2022-02-08 | — | — | CN | disclosed |