Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 5/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108916 | 0.84 | CYP2A6 (0.48) | ADORA2BADORA2ANQO2HSP90AA1HSP90AB1 | |
| SCHEMBL1369224 | 0.82 | CSNK1A1 (0.46) | ATRADORA2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL32688631 | 0.80 | ADORA2A (0.44) | ATRADORA2BADORA2ANQO2ADORA1 | |
| SCHEMBL22820591 | 0.80 | ADORA2A (0.44) | ATRADORA2BADORA2ANQO2ADORA1 | |
| SCHEMBL30175973 | 0.78 | PLAU (0.41) | ATR | |
| SCHEMBL27893934 | 0.78 | CYP2A6 (0.56) | ATRADORA2AHSP90AA1HSP90AB1PTK2 | |
| SCHEMBL30206207 | 0.78 | CYP2A6 (0.56) | ATRADORA2AHSP90AA1HSP90AB1PTK2 | |
| SCHEMBL29886664 | 0.77 | ATR (0.71) | ATRHSP90AA1HSP90AB1PTK2CYP2A6 | |
| SCHEMBL16425256 | 0.76 | PIK3CA (0.41) | CDK5 | |
| SCHEMBL21266835 | 0.75 | ATR (0.56) | ATRHSP90AA1HSP90AB1PTK2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611900-B | Imidazole pyrazinone fluorescein and preparation method thereof | 中国科学院深圳先进技术研究院 | 2024-04-26 | — | — | CN | disclosed |