Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NCF1 | P14598 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29219488 | 0.86 | POLB (0.53) | POLBMAOBMAOASMN1; SMN2TDP1 | |
| SCHEMBL29219450 | 0.86 | POLB (0.53) | POLBKDM4EMAOBMAOAALDH1A1 | |
| SCHEMBL28438033 | 0.84 | POLB (0.51) | POLBMAPTGAASMN1; SMN2HTT | |
| SCHEMBL31677954 | 0.82 | POLB (0.49) | POLBNCF1KDM4EMAPTMAOA | |
| SCHEMBL29559196 | 0.82 | KDM4E (0.54) | POLBNCF1KDM4EMAPTALDH1A1 | |
| SCHEMBL25523741 | 0.82 | KDM4E (0.54) | POLBNCF1KDM4EMAPTALDH1A1 | |
| SCHEMBL30762576 | 0.78 | HTT (0.56) | POLBNCF1KDM4EMAPTALDH1A1 | |
| SCHEMBL6534275 | 0.75 | POLB (0.43) | POLBMAOBMAOASMN1; SMN2 | |
| SCHEMBL30285349 | 0.72 | NPC1 (0.45) | KDM4EMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28719918 | 0.71 | KDM4E (0.49) | NCF1KDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117945995-A | Alkylated nitrogen-containing heterocyclic compound and preparation method and application thereof | 中国科学院青海盐湖研究所 | 2024-04-30 | — | — | CN | disclosed |