⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000369 | 0.72 | — | — | |
| SCHEMBL5381298 | 0.72 | — | — | |
| SCHEMBL294440 | 0.72 | — | — | |
| SCHEMBL6842946 | 0.71 | — | — | |
| SCHEMBL23104 | 0.67 | — | — | |
| SCHEMBL946203 | 0.67 | — | — | |
| SCHEMBL3278584 | 0.62 | — | — | |
| Carbon Tetrachloride SCHEMBL3648805 | 0.61 | — | — | |
| Carbon Tetrachloride SCHEMBL100 | 0.61 | — | — | |
| Carbon Tetrachloride SCHEMBL8874630 | 0.61 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956977-B | Biphenyl compound, pharmaceutical composition, and preparation methods and applications thereof | 朗捷睿(苏州)生物科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| WO-2023236924-A1 | BIPHENYL COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF | 朗捷睿(苏州)生物科技有限公司 | 2023-12-14 | — | — | WO | claimed |
| CN-114956977-A | Biphenyl compound, pharmaceutical composition, preparation method and application thereof | 朗捷睿(苏州)生物科技有限公司 | 2022-08-30 | — | — | CN | claimed |
| EP-3957627-B1 | 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | SHIONOGI & CO (JP) | 2024-06-19 | — | — | EP | disclosed |
| CN-114956977-B | Biphenyl compound, pharmaceutical composition, and preparation methods and applications thereof | 朗捷睿(苏州)生物科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| WO-2024053650-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST DIACYLGLYCEROL KINASE α AND/OR ζ, AND PHARMACEUTICAL USE THEREOF | 小野薬品工業株式会社 | 2024-03-14 | — | — | WO | disclosed |
| WO-2023236924-A1 | BIPHENYL COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF | 朗捷睿(苏州)生物科技有限公司 | 2023-12-14 | — | — | WO | disclosed |
| CN-114956977-A | Biphenyl compound, pharmaceutical composition, preparation method and application thereof | 朗捷睿(苏州)生物科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-110072862-B | Bicyclic nitrogen-containing heterocyclic derivative and pharmaceutical composition containing the same | 盐野义制药株式会社 | 2022-05-13 | — | — | CN | disclosed |
| CN-114106016-A | Phenylpyrazoline derivative or salt thereof, composition and application thereof | 海利尔药业集团股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| EP-3957627-A1 | 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Shionogi & Co., Ltd (JP) | 2022-02-23 | — | — | EP | disclosed |
| US-5945381-A | Herbicidal heterocyclically annulated benzoylisothiazoles | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |
| EP-0898570-A1 | HERBICIDAL HETEROCYCLICALLY SUBSTITUTED BENZOYLISOTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-03 | — | — | EP | disclosed |
| EP-0897385-A1 | HERBICIDAL HETEROCYCLICALLY ANNULATED BENZOYLISOTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-02-24 | — | — | EP | disclosed |
| EP-0897384-A1 | HERBICIDAL BENZOYLISOTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-02-24 | — | — | EP | disclosed |
| EP-0882715-A1 | NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997038996-A1 | HERBICIDAL HETEROCYCLICALLY SUBSTITUTED BENZOYLISOTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-23 | — | — | WO | disclosed |
| WO-1997038988-A1 | HERBICIDAL HETEROCYCLICALLY ANNULATED BENZOYLISOTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-23 | — | — | WO | disclosed |
| WO-1997038987-A1 | HERBICIDAL BENZOYLISOTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-23 | — | — | WO | disclosed |
| US-4518413-A | Poly-phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-21 | — | — | US | disclosed |