Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149297 | 0.84 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3CYP2D6ADRB1 | |
| SCHEMBL38661590 | 0.84 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3ADRB2NCF1 | |
| SCHEMBL14663800 | 0.82 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3ADRB2NCF1 | |
| SCHEMBL5631907 | 0.81 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6ROCK2 | |
| SCHEMBL5631902 | 0.81 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6ROCK2 | |
| SCHEMBL5631151 | 0.81 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6ADRB1 | |
| SCHEMBL5632263 | 0.81 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6ADRB1 | |
| SCHEMBL5631142 | 0.81 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6ADRB1 | |
| SCHEMBL30309502 | 0.81 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6ROCK2 | |
| SCHEMBL5632800 | 0.81 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915903-A | Compounds for the treatment of neurodegenerative, degenerative and metabolic disorders and uses thereof | 佛罗里达大学研究基金会公司 | 2024-04-19 | — | — | CN | disclosed |