Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 8/20 | 0.34 |
| ▸ | F9 | P00740 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30463633 | 1.00 | HRH3 (0.34) | HRH3CNR2F9F10ACACB | |
| SCHEMBL30463573 | 0.81 | SCD (0.36) | F9F10CDK4CCND1 | |
| SCHEMBL30463611 | 0.77 | HRH3 (0.33) | HRH3ACACBKDM4EMEN1ALDH1A1 | |
| SCHEMBL29225246 | 0.77 | HRH3 (0.33) | HRH3ACACBKDM4EMEN1ALDH1A1 | |
| SCHEMBL29225248 | 0.77 | HRH3 (0.33) | HRH3ACACBKDM4EMEN1ALDH1A1 | |
| SCHEMBL29225169 | 0.76 | ALK (0.52) | — | |
| SCHEMBL29225153 | 0.76 | SMO (0.38) | HRH3CNR2KDM4EMEN1ALDH1A1 | |
| SCHEMBL30463581 | 0.76 | SMO (0.38) | HRH3CNR2KDM4EMEN1ALDH1A1 | |
| SCHEMBL29225157 | 0.76 | SMO (0.38) | HRH3CNR2KDM4EMEN1ALDH1A1 | |
| SCHEMBL15061924 | 0.73 | HRH3 (0.42) | HRH3CNR2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514799-A | Wee1 inhibitor, composition and application thereof | 星希尔生物科技(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |