Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 12/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.46 |
| ▸ | CCND3 | P30281 | 9/20 | 0.46 |
| ▸ | CCND1 | P24385 | 8/20 | 0.46 |
| ▸ | CDK4 | P11802 | 8/20 | 0.46 |
| ▸ | CDK2 | P24941 | 7/20 | 0.46 |
| ▸ | CDK1 | P06493 | 5/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 8/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.44 |
| ▸ | CDK9 | P50750 | 4/20 | 0.44 |
| ▸ | CDK7 | P50613 | 3/20 | 0.43 |
| ▸ | CCNH | P51946 | 3/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29226305 | 0.90 | CDK6 (0.49) | CDK6CCNA2CCND3CCND1CDK4 | |
| SCHEMBL29226263 | 0.89 | PLK1 (0.51) | CDK6CCNA2CCND3CCND1CDK4 | |
| SCHEMBL29246619 | 0.88 | CDK6 (0.48) | CDK6CCNA2CCND3CCND1CDK4 | |
| SCHEMBL29226349 | 0.88 | TNK2 (0.51) | CCNA2CDK2CDK1TNK2 | |
| SCHEMBL29227024 | 0.87 | CDK6 (0.46) | CDK6CCNA2CCND3CCND1CDK4 | |
| SCHEMBL29226288 | 0.87 | TNK2 (0.47) | CDK6CCNA2CCND3CCND1CDK4 | |
| SCHEMBL29227026 | 0.87 | EGFR (0.46) | CDK6CCNA2CCND3CCND1CDK4 | |
| SCHEMBL29227028 | 0.86 | ALK (0.46) | CDK6CCNA2CCND3CCND1CDK4 | |
| SCHEMBL29226245 | 0.86 | CDK6 (0.44) | CDK6CCNA2CCND3CCND1CDK4 | |
| SCHEMBL29226364 | 0.85 | CDK6 (0.44) | CDK6CCNA2CCND3CCND1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658987-A | Compounds as PLK1 inhibitors, and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-03-08 | — | — | CN | disclosed |