Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 11/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29226390 | 0.89 | TNK2 (0.42) | TNK2IGF1RCDK2ALKEGFR | |
| SCHEMBL29226349 | 0.87 | TNK2 (0.51) | TNK2CDK2ALKEGFR | |
| SCHEMBL29226660 | 0.84 | PLK1 (0.43) | CDK2 | |
| SCHEMBL29226360 | 0.83 | PLK1 (0.41) | CDK2 | |
| SCHEMBL29226263 | 0.81 | PLK1 (0.51) | CDK2ALK | |
| SCHEMBL30900447 | 0.81 | PLK1 (0.39) | CDK2 | |
| SCHEMBL29226364 | 0.81 | CDK6 (0.44) | TNK2CDK2EGFR | |
| SCHEMBL29226288 | 0.80 | TNK2 (0.47) | TNK2CDK2EGFR | |
| SCHEMBL29227026 | 0.80 | EGFR (0.46) | TNK2CDK2EGFR | |
| SCHEMBL29227028 | 0.80 | ALK (0.46) | TNK2CDK2ALKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658987-A | Compounds as PLK1 inhibitors, and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-03-08 | — | — | CN | disclosed |