Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.30 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30900343 | 1.00 | CHRM4 (0.39) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL30900290 | 0.87 | CHRM4 (0.39) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL29226246 | 0.87 | CHRM4 (0.39) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL30900381 | 0.87 | SOS1 (0.39) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL30900418 | 0.86 | CHRM4 (0.37) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL29226658 | 0.86 | CHRM4 (0.37) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL22471199 | 0.76 | MAPT (0.46) | — | |
| SCHEMBL22471200 | 0.76 | MAPT (0.46) | — | |
| SCHEMBL1527170 | 0.75 | MAPT (0.53) | — | |
| Hydrochloric Acid SCHEMBL1527169 | 0.74 | MAPT (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658987-A | Compounds as PLK1 inhibitors, and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-03-08 | — | — | CN | disclosed |