Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227193 | 1.00 | NPC1 (0.61) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL29227102 | 0.90 | NPC1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL29227096 | 0.90 | NPC1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6499271 | 0.84 | POLB (0.56) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6496200 | 0.82 | MEN1 (0.55) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6491093 | 0.81 | MEN1 (0.54) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6502160 | 0.81 | MEN1 (0.47) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10902286 | 0.80 | NPC1 (0.79) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2604927 | 0.80 | MAPT (0.61) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL6498396 | 0.80 | MAPT (0.61) | NPC1RAB9AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |