Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.59 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.46 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30822343 | 1.00 | CRBN (0.59) | CRBNGSPT1CSNK1A1IKZF2IKZF1 | |
| SCHEMBL27208265 | 0.88 | CRBN (0.54) | CRBNGSPT1IKZF2IKZF1 | |
| SCHEMBL30139705 | 0.88 | CRBN (0.54) | CRBNGSPT1IKZF2IKZF1 | |
| SCHEMBL24123455 | 0.84 | CRBN (0.55) | CRBNIKZF2 | |
| SCHEMBL27090524 | 0.83 | CRBN (0.66) | CRBNGSPT1CSNK1A1 | |
| SCHEMBL27208467 | 0.83 | CRBN (0.66) | CRBN | |
| SCHEMBL30822397 | 0.83 | CRBN (0.66) | CRBN | |
| SCHEMBL30007020 | 0.83 | CRBN (0.66) | CRBNGSPT1CSNK1A1 | |
| SCHEMBL29369888 | 0.82 | CRBN (0.67) | CRBN | |
| SCHEMBL22291530 | 0.82 | CRBN (0.67) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836299-A | Novel bifunctional heterocyclic compounds with Bruton tyrosine kinase decomposition via ubiquitin proteasome pathway and uses thereof | 韩国化学研究院 | 2024-04-05 | — | — | CN | disclosed |