Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Diacetamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diacetamide SCHEMBL635653 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNCRBNTAS2R38 | |
| Diacetamide SCHEMBL29227696 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNCRBNTAS2R38 | |
| Diacetamide SCHEMBL29069322 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNCRBNTAS2R38 | |
| Diacetamide SCHEMBL28386543 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNCRBNTAS2R38 | |
| Diacetamide SCHEMBL28387133 | 0.92 | — | — | |
| Diacetamide SCHEMBL97089 | 0.88 | — | — | |
| Diacetamide SCHEMBL27620016 | 0.85 | CRBN (0.50) | FFAR3LCKFYNCRBNTAS2R38 | |
| Diacetamide SCHEMBL31365420 | 0.84 | — | — | |
| Diacetamide SCHEMBL31454113 | 0.84 | — | — | |
| Diacetamide SCHEMBL5457636 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117965155-B | Acidizing, yield increasing and injection increasing agent for oil field | 新疆中海科技有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-117965155-A | Acidizing, yield increasing and injection increasing agent for oil field | 新疆中海科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117965155-B | Acidizing, yield increasing and injection increasing agent for oil field | 新疆中海科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-117965155-A | Acidizing, yield increasing and injection increasing agent for oil field | 新疆中海科技有限公司 | 2024-05-03 | — | — | CN | disclosed |