Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | GFER | P55789 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2866143 | 0.94 | TAAR1 (0.59) | TAAR1TSHRTDP1GFERALDH1A1 | |
| Ethane SCHEMBL7209292 | 0.94 | TAAR1 (0.59) | TAAR1TSHRTDP1GFERALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL11510939 | 0.94 | TAAR1 (0.59) | TAAR1TSHRTDP1GFERALDH1A1 | |
| SCHEMBL6486399 | 0.89 | CYP3A4 (0.58) | TAAR1TSHRTDP1GFERALDH1A1 | |
| SCHEMBL19139640 | 0.89 | CYP3A4 (0.58) | TAAR1TSHRTDP1GFERALDH1A1 | |
| SCHEMBL19139628 | 0.89 | CYP3A4 (0.58) | TAAR1TSHRTDP1GFERALDH1A1 | |
| SCHEMBL11127394 | 0.89 | GFER (0.74) | TAAR1TSHRTDP1GFERALDH1A1 | |
| SCHEMBL4613103 | 0.89 | CYP3A4 (0.74) | TAAR1TSHRTDP1GFERALDH1A1 | |
| SCHEMBL31409202 | 0.83 | TSHR (0.48) | TAAR1TSHRTDP1GFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118147732-A | Two-dimensional structure (PEA)2PbBr4Rapid preparation method of large-size single crystal scintillator | 中山大学 | 2024-06-07 | — | — | CN | disclosed |