Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 13/20 | 0.68 |
| ▸ | DRD4 | P21917 | 10/20 | 0.64 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24984557 | 0.90 | GRM2 (0.67) | GRM2DRD4CXCR3LMNAGAA | |
| SCHEMBL30163906 | 0.88 | GRM2 (0.64) | GRM2DRD4CXCR3LMNAGAA | |
| SCHEMBL24984230 | 0.85 | GRM2 (0.67) | GRM2DRD4CXCR3LMNAGAA | |
| SCHEMBL24984556 | 0.84 | GRM2 (0.60) | GRM2DRD4CXCR3LMNAGAA | |
| SCHEMBL30164209 | 0.84 | GRM2 (0.60) | GRM2DRD4CXCR3LMNAGAA | |
| SCHEMBL4143642 | 0.82 | GRM2 (0.76) | GRM2DRD4CXCR3LMNAGAA | |
| SCHEMBL4151427 | 0.82 | GRM2 (0.76) | GRM2DRD4CXCR3LMNAGAA | |
| SCHEMBL5156990 | 0.81 | GRM2 (0.81) | GRM2DRD4LMNAGAAPOLB | |
| SCHEMBL4139885 | 0.81 | GRM2 (1.00) | GRM2DRD4CXCR3LMNAGAA | |
| SCHEMBL4138559 | 0.80 | GRM2 (1.00) | GRM2DRD4LMNAGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159530-A | Compounds for the treatment of pain, in particular neuropathic pain and/or other diseases or disorders associated with AT2R and/or AT2R mediated signalling | 康福治疗有限公司 | 2024-06-07 | — | — | CN | disclosed |