Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25349812 | 0.88 | KMT2A (0.47) | POLBKMT2AMAPTCYP1A2GAA | |
| SCHEMBL23291730 | 0.84 | POLB (0.58) | POLBKMT2AMAPTCYP1A2GAA | |
| SCHEMBL7659597 | 0.82 | ELANE (0.51) | POLBKMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL27851443 | 0.82 | POLB (0.56) | POLBKMT2AMAPTCYP1A2GAA | |
| SCHEMBL28151813 | 0.81 | POLB (0.68) | POLBKMT2AMAPTCYP1A2GAA | |
| SCHEMBL23291774 | 0.81 | POLB (0.63) | POLBKMT2AMAPTCYP1A2GAA | |
| SCHEMBL25346256 | 0.79 | F2 (0.50) | POLBMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL29254109 | 0.78 | KMT2A (0.46) | POLBKMT2AMAPTCYP1A2GAA | |
| SCHEMBL29237468 | 0.77 | POLB (0.51) | POLBKMT2AMAPTCYP1A2GAA | |
| SCHEMBL27038977 | 0.77 | MAPT (0.47) | POLBKMT2AMAPTCYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |