Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 4/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.35 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967817 | 1.00 | RHEB (0.38) | RHEBBRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30967777 | 0.88 | EPAS1 (0.39) | RHEBBRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29237705 | 0.88 | EPAS1 (0.39) | RHEBBRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27264863 | 0.88 | EPAS1 (0.39) | RHEBBRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29337812 | 0.85 | BRD4 (0.38) | RHEBBRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27275971 | 0.85 | BRD4 (0.36) | RHEBBRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30938238 | 0.85 | BRD4 (0.38) | RHEBBRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30217041 | 0.83 | EPAS1 (0.34) | RHEBBRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29237270 | 0.83 | EPAS1 (0.34) | RHEBBRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29336748 | 0.81 | JAK2 (0.36) | BRD4EPAS1HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |