Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.54 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237588 | 1.00 | DPP8 (0.54) | DPP8DPP7DPP9ABHD6TMEM97 | |
| SCHEMBL30967882 | 1.00 | DPP8 (0.54) | DPP8DPP7DPP9ABHD6TMEM97 | |
| SCHEMBL31129893 | 0.79 | TMEM97 (0.63) | ABHD6TMEM97SIGMAR1HRH1HRH3 | |
| SCHEMBL7005876 | 0.79 | TMEM97 (0.63) | ABHD6TMEM97SIGMAR1HRH1HRH3 | |
| SCHEMBL30217207 | 0.78 | TMEM97 (0.37) | DPP8DPP7DPP9TMEM97SIGMAR1 | |
| SCHEMBL25258146 | 0.76 | DPP7 (0.66) | DPP8DPP7DPP9ABHD6NAMPT | |
| SCHEMBL20336588 | 0.75 | HPGD (0.49) | DPP7DPP4 | |
| SCHEMBL20336587 | 0.75 | HPGD (0.49) | DPP7DPP4 | |
| SCHEMBL31432958 | 0.75 | DPP8 (0.62) | DPP8DPP7DPP9ABHD6DPP4 | |
| SCHEMBL31432838 | 0.75 | DPP8 (0.62) | DPP8DPP7DPP9ABHD6DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |