Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2921755 | 0.85 | MAPT (0.53) | MAPTLMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL2921752 | 0.85 | MAPT (0.53) | MAPTLMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL2921757 | 0.85 | MAPT (0.53) | MAPTLMNASMN1; SMN2ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL3753335 | 0.84 | MAPT (0.52) | MAPTLMNASMN1; SMN2ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL3753337 | 0.84 | MAPT (0.52) | MAPTLMNASMN1; SMN2ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL3753334 | 0.84 | MAPT (0.52) | MAPTLMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL9722709 | 0.84 | MAPT (0.63) | MAPTLMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL17538570 | 0.83 | MAPT (0.65) | MAPTLMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL27542697 | 0.81 | PTGDR2 (0.64) | MAPTLMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7778630 | 0.81 | MAPT (0.66) | MAPTLMNASMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222160-A2 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | Pharmaxis Ltd. (AU) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009066152-A2 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD. (US) | 2009-05-28 | — | — | WO | disclosed |