Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 6/20 | 0.49 |
| ▸ | AURKA | O14965 | 5/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.46 |
| ▸ | KIT | P10721 | 3/20 | 0.45 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CSK | P41240 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30394056 | 1.00 | PDGFRB (0.49) | PDGFRBAURKAAURKBKITKDR | |
| SCHEMBL30394353 | 0.93 | PDGFRB (0.45) | PDGFRBAURKAAURKBKITKDR | |
| SCHEMBL26534849 | 0.93 | PDGFRB (0.45) | PDGFRBAURKAAURKBKITKDR | |
| SCHEMBL30394725 | 0.93 | KDR (0.52) | KITKDREGFR | |
| SCHEMBL29238265 | 0.93 | KDR (0.52) | KITKDREGFR | |
| SCHEMBL26102438 | 0.91 | AURKA (0.49) | PDGFRBAURKAAURKBKITKDR | |
| SCHEMBL30393851 | 0.91 | AURKA (0.49) | PDGFRBAURKAAURKBKITKDR | |
| SCHEMBL29238239 | 0.90 | PDGFRB (0.45) | PDGFRBKITKDREGFR | |
| SCHEMBL30393959 | 0.90 | PDGFRB (0.45) | PDGFRBKITKDREGFR | |
| SCHEMBL26102091 | 0.90 | PDGFRB (0.48) | PDGFRBAURKAAURKBKITKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |