Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | BRAF | P15056 | 8/20 | 0.49 |
| ▸ | RAF1 | P04049 | 6/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.49 |
| ▸ | FLT4 | P35916 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 3/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30394611 | 1.00 | KDR (0.54) | KDRBRAFRAF1PDGFRBFLT4 | |
| SCHEMBL29238333 | 0.97 | KDR (0.49) | KDRBRAFRAF1PDGFRBFLT4 | |
| SCHEMBL30394615 | 0.97 | KDR (0.49) | KDRBRAFRAF1PDGFRBFLT4 | |
| SCHEMBL26102182 | 0.93 | KDR (0.51) | KDRBRAFRAF1PDGFRBFLT4 | |
| SCHEMBL26102366 | 0.93 | KDR (0.51) | KDRBRAFRAF1PDGFRBFLT4 | |
| SCHEMBL26102568 | 0.90 | KDR (0.53) | KDRBRAFRAF1PDGFRBFLT4 | |
| SCHEMBL30394038 | 0.90 | BRAF (0.48) | KDRBRAFRAF1PDGFRBFLT4 | |
| SCHEMBL29238227 | 0.90 | BRAF (0.48) | KDRBRAFRAF1PDGFRBFLT4 | |
| SCHEMBL26102818 | 0.89 | EGFR (0.54) | KDRBRAFRAF1PDGFRBFLT4 | |
| SCHEMBL26100255 | 0.89 | KDR (0.49) | KDRBRAFPDGFRBFLT4AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |