Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | MERTK | Q12866 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 9/20 | 0.44 |
| ▸ | KDR | P35968 | 7/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.44 |
| ▸ | FLT1 | P17948 | 4/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 9/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30394321 | 1.00 | KIT (0.47) | KITAXLTYRO3MERTKFLT4 | |
| SCHEMBL30394725 | 0.91 | KDR (0.52) | KITKDREGFR | |
| SCHEMBL29238265 | 0.91 | KDR (0.52) | KITKDREGFR | |
| SCHEMBL30891790 | 0.91 | KDR (0.46) | KITAXLTYRO3MERTKFLT4 | |
| SCHEMBL26102350 | 0.91 | KDR (0.46) | KITAXLTYRO3MERTKFLT4 | |
| SCHEMBL26536043 | 0.91 | KDR (0.46) | KITAXLTYRO3MERTKFLT4 | |
| SCHEMBL30394353 | 0.90 | PDGFRB (0.45) | KITFLT4KDREGFRPDGFRB | |
| SCHEMBL30393959 | 0.90 | PDGFRB (0.45) | KITFLT4KDREGFRPDGFRB | |
| SCHEMBL29238239 | 0.90 | PDGFRB (0.45) | KITFLT4KDREGFRPDGFRB | |
| SCHEMBL26534849 | 0.90 | PDGFRB (0.45) | KITFLT4KDREGFRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |