Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.42 |
| ▸ | FLT4 | P35916 | 4/20 | 0.42 |
| ▸ | BRAF | P15056 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 3/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30393873 | 1.00 | KIT (0.48) | KITROCK2KDRPDGFRBFLT4 | |
| SCHEMBL29238234 | 1.00 | KIT (0.48) | KITROCK2KDRPDGFRBFLT4 | |
| SCHEMBL26535819 | 1.00 | KIT (0.48) | KITROCK2KDRPDGFRBFLT4 | |
| SCHEMBL30891762 | 1.00 | KIT (0.48) | KITROCK2KDRPDGFRBFLT4 | |
| SCHEMBL26100776 | 1.00 | KIT (0.48) | KITROCK2KDRPDGFRBFLT4 | |
| SCHEMBL30891761 | 1.00 | KIT (0.48) | KITROCK2KDRPDGFRBFLT4 | |
| SCHEMBL30891758 | 0.96 | KIT (0.47) | KITKDRPDGFRBFLT4BRAF | |
| SCHEMBL26101744 | 0.96 | KIT (0.47) | KITKDRPDGFRBFLT4BRAF | |
| SCHEMBL30891793 | 0.96 | KIT (0.47) | KITKDRPDGFRBFLT4BRAF | |
| SCHEMBL26099909 | 0.96 | KIT (0.47) | KITKDRPDGFRBFLT4BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |