Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.83 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.83 |
| ▸ | RGS4 | P49798 | 15/20 | 0.60 |
| ▸ | RGS8 | P57771 | 15/20 | 0.60 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tideglusib SCHEMBL676929 | 0.91 | GSK3B (1.00) | GSK3BHDAC6RGS4RGS8GSK3A | |
| Tideglusib SCHEMBL29357303 | 0.91 | GSK3B (1.00) | GSK3BHDAC6RGS4RGS8GSK3A | |
| SCHEMBL29239076 | 0.89 | GSK3B (0.81) | GSK3BHDAC6RGS4RGS8 | |
| SCHEMBL29239075 | 0.89 | GSK3B (0.81) | GSK3BHDAC6RGS4RGS8 | |
| SCHEMBL29239080 | 0.89 | GSK3B (0.81) | GSK3BHDAC6RGS4RGS8GSK3A | |
| SCHEMBL30893120 | 0.88 | GSK3B (0.76) | GSK3BHDAC6RGS4RGS8DAPK3 | |
| SCHEMBL29239094 | 0.88 | GSK3B (0.76) | GSK3BHDAC6RGS4RGS8DAPK3 | |
| SCHEMBL29239096 | 0.85 | GSK3B (0.80) | GSK3BHDAC6RGS4RGS8GSK3A | |
| SCHEMBL30893121 | 0.81 | GSK3B (0.77) | GSK3BHDAC6RGS4RGS8GSK3A | |
| SCHEMBL29239085 | 0.81 | GSK3B (0.77) | GSK3BHDAC6RGS4RGS8GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113827592-B | Application of thiadiazolidinedione compound in treating pathogenic infection | 中国科学院上海药物研究所 | 2024-06-18 | — | — | CN | disclosed |