Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30866065 | 1.00 | P2RX4 (0.52) | P2RX4ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL30866020 | 0.91 | KDM4E (0.50) | P2RX4ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL29240178 | 0.91 | KDM4E (0.50) | P2RX4ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL29240191 | 0.90 | KDM4E (0.44) | P2RX4ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL30866045 | 0.90 | KDM4E (0.44) | P2RX4ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL29240225 | 0.90 | P2RX4 (0.41) | P2RX4ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL30866012 | 0.90 | P2RX4 (0.41) | P2RX4ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL30866034 | 0.89 | P2RX4 (0.40) | P2RX4ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL29240189 | 0.89 | P2RX4 (0.40) | P2RX4ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL29240197 | 0.89 | P2RX4 (0.43) | P2RX4ALDH1A1KDM4EHPGDMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917400-A | 2-Methyl-4-quinolinone compound, and pharmaceutical composition and application thereof | 暨南大学 | 2024-04-23 | — | — | CN | disclosed |