Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924163 | 1.00 | MAPT (0.37) | MAPTALDH1A1KDM4EGAAMEN1 | |
| Bromide SCHEMBL2921153 | 0.99 | MAPT (0.36) | MAPTALDH1A1KDM4EGAAMEN1 | |
| Bromide SCHEMBL2923036 | 0.99 | MAPT (0.36) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL13717110 | 0.93 | MAPT (0.33) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL2917502 | 0.87 | MEN1 (0.33) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL2917508 | 0.87 | MEN1 (0.33) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL4582953 | 0.86 | MEN1 (0.36) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| Bromide SCHEMBL2918124 | 0.86 | MEN1 (0.33) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL13716916 | 0.86 | MEN1 (0.39) | MEN1KMT2ALMNAMAPK1 | |
| Bromide SCHEMBL2918129 | 0.86 | MEN1 (0.33) | MAPTALDH1A1KDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1647548-B1 | Dictionic bishydrazones, dyeingcompositions containig at least one of these compounds, process of their preparation and uses thereoff | OREAL (FR) | 2010-08-25 | — | — | EP | claimed |
| EP-1647548-A1 | Dictionic bishydrazones, dyeingcompositions containig at least one of these compounds, process of their preparation and uses thereoff | L'OREAL S.A. (FR) | 2006-04-19 | — | — | EP | claimed |
| EP-1647548-B1 | Dictionic bishydrazones, dyeingcompositions containig at least one of these compounds, process of their preparation and uses thereoff | OREAL (FR) | 2010-08-25 | — | — | EP | disclosed |
| EP-1647548-A1 | Dictionic bishydrazones, dyeingcompositions containig at least one of these compounds, process of their preparation and uses thereoff | L'OREAL S.A. (FR) | 2006-04-19 | — | — | EP | disclosed |