Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 3/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.54 |
| ▸ | CDK9 | P50750 | 2/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.54 |
| ▸ | CDK14 | O94921 | 12/20 | 0.54 |
| ▸ | CCNY | Q8ND76 | 12/20 | 0.54 |
| ▸ | CDK2 | P24941 | 6/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.54 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.54 |
| ▸ | CDK4 | P11802 | 2/20 | 0.54 |
| ▸ | CDK1 | P06493 | 2/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.54 |
| ▸ | CASK | O14936 | 1/20 | 0.54 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.54 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.54 |
| ▸ | MAK | P20794 | 1/20 | 0.54 |
| ▸ | CDK11B | P21127 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.54 |
| ▸ | CCND3 | P30281 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29108698 | 0.86 | CDK5 (0.55) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL22594270 | 0.86 | CDK14 (0.59) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL2425448 | 0.84 | CDK5 (0.55) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL22582171 | 0.84 | CDK5 (0.54) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL25992121 | 0.84 | CDK5 (0.54) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL22594259 | 0.82 | CDK5 (0.52) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL22594266 | 0.81 | CDK14 (0.52) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL30915451 | 0.81 | CDK5 (0.60) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL22022383 | 0.80 | CDK5 (0.59) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL22594271 | 0.80 | CDK14 (0.50) | CDK5CCNT1CDK9CDK5R1CDK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008058-B | Prodrugs of CDK inhibitors for the treatment of cancer | 润佳（苏州）医药科技有限公司 | 2024-07-05 | — | — | CN | disclosed |