Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29585770 | 1.00 | POLB (0.42) | POLBEPHX2THRBROCK2ROCK1 | |
| SCHEMBL29583762 | 0.90 | POLB (0.44) | POLBEPHX2THRBROCK2ROCK1 | |
| SCHEMBL24423578 | 0.90 | POLB (0.46) | POLBEPHX2THRBROCK2ROCK1 | |
| SCHEMBL24422999 | 0.90 | POLB (0.44) | POLBEPHX2THRBROCK2ROCK1 | |
| SCHEMBL29585078 | 0.90 | POLB (0.46) | POLBEPHX2THRBROCK2ROCK1 | |
| SCHEMBL29243422 | 0.89 | POLB (0.43) | POLBEPHX2THRBROCK2ROCK1 | |
| SCHEMBL29584984 | 0.89 | POLB (0.43) | POLBEPHX2THRBROCK2ROCK1 | |
| SCHEMBL29584948 | 0.89 | POLB (0.43) | POLBEPHX2THRBROCK2ROCK1 | |
| SCHEMBL29243835 | 0.89 | POLB (0.43) | POLBEPHX2THRBROCK2ROCK1 | |
| SCHEMBL29584936 | 0.88 | POLB (0.42) | POLBEPHX2THRBROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |