Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29243446 | 1.00 | KDM5A (0.34) | KDM5AMAPK1BACE1GNRHREPHX2 | |
| SCHEMBL29586441 | 1.00 | KDM5A (0.34) | KDM5AMAPK1BACE1GNRHREPHX2 | |
| SCHEMBL29585776 | 1.00 | KDM5A (0.34) | KDM5AMAPK1BACE1GNRHREPHX2 | |
| SCHEMBL24424120 | 1.00 | KDM5A (0.34) | KDM5AMAPK1BACE1GNRHREPHX2 | |
| SCHEMBL29243568 | 1.00 | KDM5A (0.34) | KDM5AMAPK1BACE1GNRHREPHX2 | |
| SCHEMBL24424121 | 1.00 | KDM5A (0.34) | KDM5AMAPK1BACE1GNRHREPHX2 | |
| SCHEMBL24424114 | 1.00 | KDM5A (0.34) | KDM5AMAPK1BACE1GNRHREPHX2 | |
| SCHEMBL24424115 | 1.00 | KDM5A (0.34) | KDM5AMAPK1BACE1GNRHREPHX2 | |
| SCHEMBL29243445 | 1.00 | KDM5A (0.34) | KDM5AMAPK1BACE1GNRHREPHX2 | |
| SCHEMBL25090993 | 0.94 | MAPK1 (0.32) | KDM5AMAPK1BACE1GNRHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |