Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150632 | 0.85 | CNR1 (0.43) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL19816585 | 0.80 | MEN1 (0.61) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL30398949 | 0.80 | MEN1 (0.61) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL19816588 | 0.80 | MEN1 (0.61) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL21022756 | 0.78 | MEN1 (0.59) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL4038473 | 0.77 | MEN1 (0.58) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL1685859 | 0.77 | MEN1 (0.54) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL7934857 | 0.76 | MEN1 (0.57) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL5643654 | 0.75 | KMT2A (0.71) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL12480624 | 0.75 | BDKRB1 (0.41) | CNR1PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290334-A | Preparation method of Lifeiste key intermediate | 上海医药工业研究院有限公司 | 2024-07-05 | — | — | CN | disclosed |