Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20974903 | 1.00 | SMYD2 (0.35) | SMYD2ABCB1RIPK1EP300CREBBP | |
| SCHEMBL29246122 | 1.00 | SMYD2 (0.35) | SMYD2ABCB1RIPK1EP300CREBBP | |
| SCHEMBL29246202 | 0.92 | SMYD2 (0.34) | SMYD2ABCB1MEN1KMT2A | |
| SCHEMBL30188954 | 0.92 | SMYD2 (0.34) | SMYD2ABCB1MEN1KMT2A | |
| SCHEMBL29246199 | 0.92 | SMYD2 (0.34) | SMYD2ABCB1MEN1KMT2A | |
| SCHEMBL29245984 | 0.88 | SMYD2 (0.38) | SMYD2ABCB1 | |
| SCHEMBL20974750 | 0.88 | SMYD2 (0.38) | SMYD2ABCB1 | |
| SCHEMBL29245985 | 0.88 | SMYD2 (0.38) | SMYD2ABCB1 | |
| SCHEMBL20974733 | 0.79 | SMYD2 (0.38) | SMYD2RIPK1 | |
| SCHEMBL30675380 | 0.79 | SMYD2 (0.38) | SMYD2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989321-B | KRAS G12C inhibitors | 米拉蒂治疗股份有限公司 | 2024-05-14 | — | — | CN | disclosed |