Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.56 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 6/20 | 0.43 |
| ▸ | FLT3 | P36888 | 5/20 | 0.43 |
| ▸ | FYN | P06241 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | DBH | P09172 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30910343 | 1.00 | FGFR1 (0.56) | FGFR1FGFR4HRH3SCN9ANOTUM | |
| SCHEMBL29246277 | 0.88 | FGFR1 (0.55) | FGFR1FGFR4HRH3SCN9ANOTUM | |
| SCHEMBL30910334 | 0.88 | FGFR1 (0.55) | FGFR1FGFR4HRH3SCN9ANOTUM | |
| SCHEMBL29246465 | 0.85 | FGFR1 (0.53) | FGFR1FGFR4HRH3SCN9ANOTUM | |
| SCHEMBL30910327 | 0.85 | FGFR1 (0.53) | FGFR1FGFR4HRH3SCN9ANOTUM | |
| SCHEMBL31632948 | 0.85 | FGFR1 (0.53) | FGFR1FGFR4HRH3SCN9ANOTUM | |
| SCHEMBL29246436 | 0.85 | FGFR1 (0.59) | FGFR1FGFR4HRH3SCN9ANOTUM | |
| SCHEMBL30910346 | 0.85 | FGFR1 (0.59) | FGFR1FGFR4HRH3SCN9ANOTUM | |
| SCHEMBL3541053 | 0.84 | NOTUM (0.58) | FGFR1FGFR4SCN9ANOTUMKCNH2 | |
| SCHEMBL30910329 | 0.82 | FGFR1 (0.51) | FGFR1FGFR4HRH3SCN9ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865965-B | Pyrrolopyrimidine-4-amine and pyrazolopyrimidine-4-amine derivatives, preparation method and application thereof | 贵州省天然产物研究中心 | 2024-06-28 | — | — | CN | disclosed |