Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31039332 | 0.88 | MAPT (0.57) | MAPTHPGDCYP1A2ALOX12CYP2C19 | |
| SCHEMBL29246709 | 0.84 | RECQL (0.60) | MAPTHPGDCYP1A2ALOX12CYP2C19 | |
| SCHEMBL30052762 | 0.84 | MAPT (0.60) | MAPTHPGDCYP1A2ALOX12CYP2C19 | |
| SCHEMBL4221175 | 0.84 | MAPT (0.60) | MAPTHPGDCYP1A2ALOX12CYP2C19 | |
| SCHEMBL4221172 | 0.84 | MAPT (0.60) | MAPTHPGDCYP1A2ALOX12CYP2C19 | |
| SCHEMBL29076332 | 0.83 | MAPT (0.58) | MAPTHPGDCYP1A2ALOX12CYP2C19 | |
| SCHEMBL29246711 | 0.83 | POLB (0.50) | MAPTHPGDCYP1A2ALOX12CYP2C19 | |
| SCHEMBL29246712 | 0.81 | CYP1A2 (0.57) | MAPTHPGDCYP1A2ALOX12CYP2C19 | |
| SCHEMBL8798626 | 0.81 | MAPT (0.60) | MAPTHPGDCYP1A2ALOX12CYP2C19 | |
| SCHEMBL8798630 | 0.81 | MAPT (0.60) | MAPTHPGDCYP1A2ALOX12CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118479973-A | Preparation method of 1-naphthylamine compound | 西北工业大学 | 2024-08-13 | — | — | CN | claimed |
| CN-118388325-A | Preparation method of 1-naphthol compound | 西北工业大学 | 2024-07-26 | — | — | CN | claimed |
| CN-118307411-A | Preparation method of 2-acyl naphthol compound | 西北工业大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118479973-A | Preparation method of 1-naphthylamine compound | 西北工业大学 | 2024-08-13 | — | — | CN | disclosed |
| CN-118388325-A | Preparation method of 1-naphthol compound | 西北工业大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-118307411-A | Preparation method of 2-acyl naphthol compound | 西北工业大学 | 2024-07-09 | — | — | CN | disclosed |