SCHEMBL29247883

SCHEMBL29247883

CC(C)=Cc1cc2cc(C)ccc2n1C

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.46
RXFP1 Q9HBX9 3/20 0.46
THRB P10828 1/20 0.43
LMNA P02545 8/20 0.40
TP53 P04637 5/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
POLB P06746 1/20 0.37
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29247892 0.86 MAPT (0.42) MAPTRXFP1THRBLMNAMEN1
SCHEMBL29247888 0.79 GRIN2D (0.53) MAPTMEN1KMT2A
SCHEMBL4019147 0.79 MAPT (0.49) MAPTRXFP1THRBLMNATP53
SCHEMBL18126630 0.72 KDM4E (0.44) MAPTRXFP1THRBLMNATP53
SCHEMBL29769204 0.71 MAPT (0.57) MAPTRXFP1THRBLMNATP53
SCHEMBL5985980 0.71 MAPT (0.57) MAPTRXFP1THRBLMNATP53
SCHEMBL12182 0.68 RXFP1 (0.53) MAPTRXFP1THRBLMNATP53
SCHEMBL25292537 0.68 MAPT (0.49) MAPTRXFP1THRBLMNATP53
SCHEMBL3965642 0.68 MAPT (0.49) MAPTRXFP1THRBLMNATP53
SCHEMBL29951155 0.68 MAPT (0.49) MAPTRXFP1THRBLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118255708-A Polysubstituted carbazole derivative and synthesis method thereof 重庆理工大学 2024-06-28 CN claimed
CN-118255708-A Polysubstituted carbazole derivative and synthesis method thereof 重庆理工大学 2024-06-28 CN disclosed