Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | PTK6 | Q13882 | 7/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.38 |
| ▸ | AURKA | O14965 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.38 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29691562 | 0.99 | NR3C2 (0.43) | NR3C2PTK6GPR84APPNR4A2 | |
| Hydrochloric Acid SCHEMBL26679848 | 0.99 | NR3C2 (0.43) | NR3C2PTK6GPR84APPNR4A2 | |
| Hydrochloric Acid SCHEMBL30546633 | 0.79 | APP (0.40) | PTK6APPNR4A2ERBB2AURKA | |
| Hydrochloric Acid SCHEMBL26679845 | 0.79 | APP (0.40) | PTK6APPNR4A2ERBB2AURKA | |
| SCHEMBL24600663 | 0.79 | APP (0.44) | PTK6APPNR4A2ERBB2AURKA | |
| Hydrochloric Acid SCHEMBL26679855 | 0.78 | PTK6 (0.39) | PTK6APPNR4A2ERBB2AURKA | |
| SCHEMBL24600522 | 0.78 | APP (0.41) | PTK6APPNR4A2ERBB2AURKA | |
| Hydrochloric Acid SCHEMBL30546664 | 0.77 | APP (0.43) | PTK6APPNR4A2ERBB2AURKA | |
| SCHEMBL24600519 | 0.77 | TNNI3K (0.40) | PTK6APPNR4A2ERBB2AURKA | |
| Hydrochloric Acid SCHEMBL26679816 | 0.77 | APP (0.43) | PTK6APPNR4A2ERBB2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |