Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 13/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 13/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.57 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546846 | 1.00 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP19A1ELOVL1KDM4E | |
| SCHEMBL29248958 | 0.89 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL30453166 | 0.89 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1KDM4ECYP1A2 | |
| SCHEMBL24257578 | 0.89 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1KDM4ECYP1A2 | |
| SCHEMBL30546832 | 0.89 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL30546875 | 0.88 | CYP11B1 (0.43) | CYP11B1CYP11B2CYP19A1KDM4EHSD17B10 | |
| SCHEMBL30546856 | 0.81 | PDE10A (0.38) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL30546817 | 0.81 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP19A1ELOVL1CYP1A2 | |
| SCHEMBL29248901 | 0.81 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP19A1ELOVL1CYP1A2 | |
| SCHEMBL24257687 | 0.77 | CYP11B1 (0.42) | CYP11B1CYP11B2CYP19A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670131-A | PHD inhibitor compounds, compositions, and methods of use | 阿克比治疗有限公司 | 2023-08-29 | — | — | CN | disclosed |