Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 3/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 10/20 | 0.47 |
| ▸ | JAK1 | P23458 | 10/20 | 0.47 |
| ▸ | JAK3 | P52333 | 10/20 | 0.47 |
| ▸ | TYK2 | P29597 | 4/20 | 0.47 |
| ▸ | FLT4 | P35916 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956404 | 0.91 | JAK1 (0.51) | CCNE1CDK2JAK2JAK1JAK3 | |
| SCHEMBL24852462 | 0.88 | JAK2 (0.53) | CCNE1CDK2CDK1CCNB1JAK2 | |
| SCHEMBL24852466 | 0.82 | JAK2 (0.53) | CCNE1CDK2CDK1CCNB1JAK2 | |
| SCHEMBL30956409 | 0.81 | JAK1 (0.53) | JAK2JAK1JAK3TYK2FLT4 | |
| SCHEMBL28602253 | 0.81 | IGF1R (0.49) | CDK2CDK1JAK2JAK1JAK3 | |
| Hydrochloric Acid SCHEMBL30956379 | 0.80 | FLT4 (0.57) | JAK1JAK3FLT4KDR | |
| SCHEMBL30956425 | 0.80 | JAK1 (0.51) | JAK2JAK1JAK3TYK2FLT4 | |
| SCHEMBL30956464 | 0.79 | FLT4 (0.51) | CDK2CDK1FLT4KDR | |
| SCHEMBL22097977 | 0.79 | FLT4 (0.55) | JAK2JAK1JAK3FLT4KDR | |
| SCHEMBL22098075 | 0.78 | JAK2 (0.57) | CCNE1CDK2CDK1CCNB1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290403-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-07-05 | — | — | CN | disclosed |