SCHEMBL29249366

SCHEMBL29249366

COc1cccc(COc2ccc(N(CC(=O)O)CC(=O)O)c(N(CC(=O)O)CC(=O)O)c2)c1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.62
MRGPRX4 Q96LA9 2/20 0.56
KEAP1 Q14145 1/20 0.56
NFE2L2 Q16236 1/20 0.56
FFAR1 O14842 5/20 0.52
RAB9A P51151 2/20 0.51
TP53 P04637 1/20 0.51
PKM P14618 1/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
PPARD Q03181 1/20 0.50
SLC2A1 P11166 1/20 0.50
SLC2A4 P14672 1/20 0.50
ACHE P22303 1/20 0.49
MAOA P21397 1/20 0.48
NPC1 O15118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29249355 0.87 FFAR1 (0.55) MAOBKEAP1NFE2L2FFAR1RAB9A
SCHEMBL29249358 0.86 MAOB (0.53) MAOBKEAP1NFE2L2FFAR1
SCHEMBL29249353 0.79 NPC1 (0.51) MAOBMRGPRX4FFAR1RAB9ATP53
SCHEMBL16552397 0.77 MAOB (1.00) MAOBMAOA
SCHEMBL4760103 0.77 MAOB (0.67) MAOBMRGPRX4FFAR1RAB9ATP53
SCHEMBL20961889 0.76 MAOB (0.66) MAOBMRGPRX4FFAR1RAB9ATP53
Hydrochloric Acid SCHEMBL17923757 0.76 MAOB (0.98) MAOBMAOA
Hydrochloric Acid SCHEMBL17923756 0.76 MAOB (0.98) MAOBMAOA
SCHEMBL29249363 0.76 MAPT (0.47) KEAP1NFE2L2FFAR1SMN1; SMN2
SCHEMBL3649253 0.75 MRGPRX4 (0.76) MAOBMRGPRX4RAB9ATP53PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324653-A Compound, metal compound, preparation method and application thereof, contrast agent and imaging method 四川大学 2024-07-12 CN disclosed